114 research outputs found

    That’s Not Fair: Tariff Structures for Electric Utilities with Rooftop Solar

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    Problem definition: Utility regulators are grappling to devise compensation schemes for customers who sell rooftop solar generation back to the grid, balancing environmental interests and the financial interests of utilities, solar system installers, and retail customers. This is difficult: Regulatory changes made in Nevada in 2015 to protect Nevada’s utility induced SolarCity, the market leader in solar systems, to suspend local operations. We show that the choice of utility tariff structure is crucial to achieving socially desirable objectives. Academic/practical relevance: It is important for regulators to understand how tariff structure interacts with social objectives. This has implications for consumers, regulators, and industry. Methodology: We use a sequential game to analyze the regulator’s social welfare maximization problem in a market with a regulated utility; an unregulated, price-setting, profit-maximizing solar system installer; and customers who endogenously determine whether to adopt solar or not, based on utility tariffs, solar prices, and their heterogeneous usage profiles and generation potentials. Results: We illustrate that the effectiveness of tariff structures is not governed simply by the number of free tariff parameters, but by the functions these parameters serve. In particular, an effective tariff must discriminate among customer usage tiers and between customers with and without rooftop solar to achieve socially desirable outcomes. We present a tariff structure with these two characteristics and show how it can be implemented as a simple buy-all, sell-all tariff while retaining its favorable properties. We illustrate our findings numerically using data from Nevada and New Mexico, two states grappling with this issue. Managerial implications: Many utilities in the United States operate tariff structures that are missing at least one of the two identified features. Regulators must overhaul these tariff structures to adequately safeguard all stakeholders

    Optimal Structural Results for Assemble-to-Order Generalized M-Systmes

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    Cataloged from PDF version of article.We consider an assemble-to-order generalized M-system with multiple components and multiple products, batch ordering of components, random lead times, and lost sales. We model the system as an in nite-horizon Markov decision process and seek an optimal control policy, which speci es when a batch of components should be produced and whether an arriving demand for each product should be satis ed. To facilitate our analysis, we introduce new functional characterizations for convexity and submodularity with respect to certain non-unitary directions. These help us characterize optimal inventory replenishment and allocation policies under a mild condition on component batch sizes via a new type of policy: lattice-dependent base-stock and lattice-dependent rationing

    Real-time delay announcement under competition

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    Internet-based technology enables firms to disseminate real-time delay information to delay-sensitive customers. We study how such delay announcements impact service providers in a competitive environment with two service providers who compete for market share. We model the service providers' strategies based on an endogenous timing game, investigating strategies that emerge in equilibrium. We determine the service providers' market shares under the various game outcomes by analyzing continuous-time Markov chains, which capture customers' joining decisions, and by developing a novel computational technique to analyze the intractable asymmetric Join-the-Shortest Queue system, providing bounds on the market shares. We find that only the lower capacity service provider announces its real-time delay under intermediate system loads and highly imbalanced capacities. However, for most parameter settings, the mere presence of a competitor induces both providers to announce delays in equilibrium, leaving customers better off on average. We relate our findings to the single-provider delay announcement literature by discussing the impact of competition on service providers, delay announcement technology firms, and customers

    Optimal control of serial, multi-echelon inventory/production systems with periodic batching

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    We consider a single-item, periodic-review, serial, multi-echelon inventory system, with linear inventory holding and penalty costs. In order to facilitate shipment consolidation and capacity planning, we assume the system has implemented periodic batching: each stage is allowed to order at given equidistant times. Further, for each stage except the most downstream one, the reorder interval is assumed to be an integer multiple of the reorder interval of the next downstream stage. This reflects the fact that the further upstream in a supply chain, the higher setup times and costs tend to be, and thus stronger batching is desired. Our model with periodic batching is a direct generalization of the serial, multi-echelon model of Clark and Scarf (1960). For this generalized model, we prove the optimality of basestock policies, we derive Newsboy-type characterizations for the optimal basestock levels, and we describe an efficient exact solution procedure for the case with mixed Erlang demands. Finally, we present extensions to assembly systems and to systems with a modified fill rate constraint instead of backorder costs. Subject classification: Inventory/Production: Multi-echelon, stochastic demand, periodic batching, optimal policies.

    Experimental Results Indicating Lattice-Dependent Policies May Be Optimal for General Assemble-To-Order Systems

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    We consider an assemble-to-order (ATO) system with multiple products, multiple components which may be demanded in different quantities by different products, possible batch ordering of components, random lead times, and lost sales. We model the system as an infinite-horizon Markov decision process under the average cost criterion. A control policy specifies when a batch of components should be produced, and whether an arriving demand for each product should be satisfied. Previous work has shown that a lattice-dependent base-stock and lattice-dependent rationing (LBLR) policy is an optimal stationary policy for a special case of the ATO model presented here (the generalized M-system). In this study, we conduct numerical experiments to evaluate the use of an LBLR policy for our general ATO model as a heuristic, comparing it to two other heuristics from the literature: a state-dependent base-stock and state-dependent rationing (SBSR) policy, and a fixed base-stock and fixed rationing (FBFR) policy. Remarkably, LBLR yields the globally optimal cost in each of more than 22,500 instances of the general problem, outperforming SBSR and FBFR with respect to both objective value (by up to 2.6% and 4.8%, respectively) and computation time (by up to three orders and one order of magnitude, respectively) in 350 of these instances (those on which we compare the heuristics). LBLR and SBSR perform significantly better than FBFR when replenishment batch sizes imperfectly match the component requirements of the most valuable or most highly demanded product. In addition, LBLR substantially outperforms SBSR if it is crucial to hold a significant amount of inventory that must be rationed. © 2015 Production and Operations Management Society

    Pallidal low‐frequency activity in dystonia after cessation of long‐term deep brain stimulation

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    Objective: This study investigates the association between pallidal low-frequency activity and motor sign severity in dystonia after chronic deep brain stimulation for several months. Methods: Local field potentials were recorded in 9 dystonia patients at 5 timepoints (T1–T5) during an OFF-stimulation period of 5 to 7 hours in parallel with clinical assessment using Burke-Fahn-Marsden Dystonia Rating Scale. A linear mixed effects model was used to investigate the potential association of motor signs with local field potential activity in the low frequency (3–12 Hz) and beta range (13–30 Hz). Results: A significant association of Burke-Fahn-Marsden Dystonia Rating Scale scores with low-frequency activity (3–12 Hz; b = 4.4; standard error = 1.5, degrees of freedom = 43, P = 0.006, 95% confidence interval, 1.3–7.5), but not beta activity (13–30 Hz) was revealed within participants across timepoints. Conclusion: Low-frequency activity is associated with dystonic motor sign severity, even months after chronic deep brain stimulation. Our findings corroborate the pathophysiological role of low-frequency activity in dystonia and highlight the potential utility as a biomarker for adaptive neuromodulation

    Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

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    Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate structural breakdown. Such an unavoidable variant of cellular demise is generally referred to as ‘accidental cell death’ (ACD). In most settings, however, cell death is initiated by a genetically encoded apparatus, correlating with the fact that its course can be altered by pharmacologic or genetic interventions. ‘Regulated cell death’ (RCD) can occur as part of physiologic programs or can be activated once adaptive responses to perturbations of the extracellular or intracellular microenvironment fail. The biochemical phenomena that accompany RCD may be harnessed to classify it into a few subtypes, which often (but not always) exhibit stereotyped morphologic features. Nonetheless, efficiently inhibiting the processes that are commonly thought to cause RCD, such as the activation of executioner caspases in the course of apoptosis, does not exert true cytoprotective effects in the mammalian system, but simply alters the kinetics of cellular demise as it shifts its morphologic and biochemical correlates. Conversely, bona fide cytoprotection can be achieved by inhibiting the transduction of lethal signals in the early phases of the process, when adaptive responses are still operational. Thus, the mechanisms that truly execute RCD may be less understood, less inhibitable and perhaps more homogeneous than previously thought. Here, the Nomenclature Committee on Cell Death formulates a set of recommendations to help scientists and researchers to discriminate between essential and accessory aspects of cell death

    Immunolocalization of cell wall polymers in grapevine (Vitis vinifera) internodes under nitrogen, phosphorus or sulfur deficiency

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    Abstract The impact on cell wall (CW) of the deficiency in nitrogen (–N), phosphorus (–P) or sulphur (–S), known to impair essential metabolic pathways, was investigated in the economically important fruit species Vitis vinifera L. Using cuttings as an experimental model a reduction in total internode number and altered xylem shape was observed. Under –N an increased internode length was also seen. CW composition, visualised after staining with calcofluor white, Toluidine blue and ruthenium red, showed decreased cellulose in all stresses and increased pectin content in recently formed internodes under –N compared to the control. Using CW-epitope specific monoclonal antibodies (mAbs), lower amounts of extensins incorporated in the wall were also observed under –N and –P conditions. Conversely, increased pectins with a low degree of methyl-esterification and richer in long linear 1,5-arabinan rhamnogalacturonan-I (RG-I) side chains were observed under –N and –P in mature internodes which, in the former condition, were able to form dimeric association through calcium ions. –N was the only condition in which 1,5-arabinan branched RG- content was not altered, as –P and –S older internodes showed, respectively, lower and higher amounts of this polymer. Higher xyloglucan content in older internodes was also observed under –N. The results suggest that impairments of specific CW components led to changes in the deposition of other polymers to promote stiffening of the CW. The unchanged extensin amount observed under –S may contribute to attenuating the effects on the CW integrity caused by this stress. Our work showed that, in organized V. vinifera tissues, modifications in a given CW component can be compensated by synthesis of different polymers and/or alternative linking between polymers. The results also pinpoint different strategies at the CW level to overcome mineral stress depending on how essential they are to cell growth and plant development
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